Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1.
The target of rapamycin (TOR) kinase coordinately regulates fundamental metabolic and cellular processes to support growth, proliferation, survival, and differentiation, and consequently it has been proposed as a therapeutic target for the treatment of cancer, metabolic disease, and aging.The TOR kinase is found in two biochemically and functionall